Beilstein J. Org. Chem.2010,6, No. 34, doi:10.3762/bjoc.6.34
and 5′-amino-2′,5′-dideoxythymidine. The title compounds may find application as antiprotozoalagents. Moreover, preliminary microscopy TEM studies of supramolecular behaviour showed that target molecules with bolaamphiphilic structures were capable of forming highly ordered assemblies, mainly
nanofibres.
Keywords: amides; antiprotozoalagents; coupling; nucleosides; self-assembly; Introduction
There are numerous reports on the synthesis and application of symmetrical and unsymmetrical α,ω-nucleobase amide-conjugated systems (Figure 1) [1][2][3][4][5][6]. These molecules are constructed usually
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Graphical Abstract
Figure 1:
Examples of symmetrical and unsymmetrical α,ω-nucleobase amide-conjugated systems.